Michael R Jacobs Selected Research

Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)

3/2007	Oral beta-lactams applied to uncomplicated infections of skin and skin structures.
6/2005	Extended release amoxicillin/clavulanate: optimizing a product for respiratory infections based on pharmacodynamic principles.
11/2004	Comparative in vitro activity of a pharmacokinetically enhanced oral formulation of amoxicillin/clavulanic acid (2000/125 mg twice daily) against 9172 respiratory isolates collected worldwide in 2000.
10/2002	Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxycillin/clavulanate.

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Michael R Jacobs Research Topics

Disease

38	Infections 08/2021 - 10/2002
11	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 04/2011
9	Pneumococcal Infections 11/2012 - 09/2002
9	Respiratory Tract Infections (Respiratory Tract Infection) 12/2007 - 02/2002
8	Pneumonia (Pneumonitis) 07/2012 - 10/2002
8	Otitis Media 07/2009 - 08/2002
6	Sepsis (Septicemia) 01/2020 - 12/2006
4	Tuberculosis (Tuberculoses) 01/2018 - 01/2004
4	Neoplasms (Cancer) 01/2017 - 01/2012
4	Bacteremia 01/2017 - 04/2007
4	Transfusion Reaction 01/2016 - 01/2006
4	Sinusitis 04/2007 - 03/2002
3	Rhinosinusitis 02/2013 - 03/2002
2	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 01/2015
2	Persistent Infection 01/2022 - 01/2017
2	Cross Infection (Nosocomial Infection) 01/2016 - 08/2005
2	Inflammation (Inflammations) 01/2016 - 11/2009
2	Wounds and Injuries (Trauma) 04/2013 - 12/2007
2	Gastroparesis 04/2012 - 01/2011
2	Staphylococcal Infections 10/2010 - 12/2004
2	Impetigo (Impetigo Contagiosa) 12/2007 - 03/2007
2	Chronic Bronchitis 04/2007 - 10/2002
2	Virus Diseases (Viral Diseases) 06/2004 - 08/2003
2	Bacterial Infections (Bacterial Infection) 01/2003 - 03/2002
1	Hypertension (High Blood Pressure) 01/2020
1	Weight Loss (Weight Reduction) 12/2018
1	Nausea 12/2018
1	Emphysema 10/2018
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2018
1	Septic Shock (Toxic Shock Syndrome) 01/2017
1	Starvation 10/2016
1	Neural Tube Defects (Exencephaly) 10/2016
1	Anemia 10/2016

Drug/Important Bio-Agent (IBA)

22	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 03/2002
11	Amoxicillin (Wymox)FDA LinkGeneric 02/2013 - 10/2002
10	Pharmaceutical PreparationsIBA 08/2021 - 09/2002
8	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 12/2007 - 10/2002
7	MacrolidesIBA 12/2008 - 02/2002
6	Carbapenems (Carbapenem Antibiotics)IBA 01/2020 - 10/2014
6	VaccinesIBA 04/2014 - 03/2005
6	Penicillins (Penicillin)FDA Link 11/2012 - 10/2002
5	beta-LactamsIBA 12/2008 - 01/2003
4	Conjugate VaccinesIBA 12/2008 - 08/2002
4	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)FDA Link 03/2007 - 10/2002
4	Anti-Infective Agents (Microbicides)IBA 06/2004 - 01/2003
3	Penicillin G (Benzylpenicillin)FDA LinkGeneric 06/2012 - 10/2008
3	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 12/2008 - 08/2003
3	Clindamycin (Cleocin)FDA LinkGeneric 12/2008 - 08/2004
3	beta-Lactamases (beta-Lactamase)IBA 04/2007 - 10/2002
3	QuinolonesIBA 10/2006 - 01/2004
3	FluoroquinolonesIBA 12/2004 - 01/2004
2	ceftazidime drug combination avibactamIBA 01/2020 - 01/2017
2	AntioxidantsIBA 08/2019 - 01/2016
2	Colistin (Coly-Mycin)FDA Link 04/2018 - 03/2016
2	EnzymesIBA 01/2018 - 07/2012
2	sulforaphaneIBA 01/2017 - 01/2016
2	IronIBA 01/2017 - 03/2016
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 09/2015 - 12/2008
2	DNA (Deoxyribonucleic Acid)IBA 04/2012 - 01/2011
2	Domperidone (Domperidon)IBA 04/2012 - 01/2011
2	Linezolid (Zyvox)FDA Link 04/2011 - 12/2004
2	AntigensIBA 12/2010 - 03/2005
2	Vancomycin FDA LinkGeneric 10/2010 - 12/2004
2	ceftobiproleIBA 08/2009 - 09/2008
2	Methicillin (Metin)FDA Link 08/2009 - 12/2007
2	Levofloxacin (Levaquin)FDA Link 12/2008 - 10/2002
2	Azithromycin (Zithromax)FDA LinkGeneric 12/2008 - 01/2004
2	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 10/2008 - 01/2004
2	Ointments (Pastes)IBA 12/2007 - 03/2007
2	Cephalosporins (Cephalosporin Antibiotics)IBA 04/2007 - 03/2007
2	Proteins (Proteins, Gene)FDA Link 04/2007 - 03/2005
2	WCK 771IBA 10/2006 - 12/2004
2	Delayed-Action PreparationsIBA 06/2005 - 11/2004
2	Clarithromycin (Biaxin)FDA LinkGeneric 01/2004 - 10/2002
1	Meropenem (Merrem)FDA LinkGeneric 08/2021
1	Aztreonam FDA LinkGeneric 01/2020
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2020
1	Hypnotics and Sedatives (Sedatives)IBA 01/2019
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	Cefepime (Maxipime)FDA LinkGeneric 01/2019
1	enmetazobactamIBA 01/2019
1	Anti-Anxiety Agents (Anxiolytics)IBA 01/2019
1	RoflumilastIBA 12/2018
1	carbapenemaseIBA 04/2018
1	Rifampin (Rifampicin)FDA LinkGeneric 01/2018
1	bedaquiline (R207910)IBA 01/2018
1	Cytochrome P-450 CYP3AIBA 01/2018
1	Rifabutin (Ansamycin)FDA Link 01/2018
1	ThymineIBA 10/2016
1	HomocysteineIBA 10/2016
1	Methionine (L-Methionine)FDA Link 10/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 10/2016

Therapy/Procedure

13	Therapeutics 01/2022 - 03/2002
3	Platelet Transfusion (Blood Platelet Transfusions) 01/2016 - 01/2006
2	Contact Lenses 01/2014 - 11/2009
2	Herniorrhaphy 04/2013 - 10/2010
2	Drug Therapy (Chemotherapy) 01/2012 - 09/2002
1	Patient Readmission 12/2018
1	Pneumonectomy (Lung Volume Reduction) 10/2018
1	Transplantation 01/2017